Testing of sperm DNA damage and clinical recommendations

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Testing of sperm DNA damage and clinical recommendations

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Agarwal et al. in their most recent paper (1) propose a clinical guideline on the use of sperm DNA damage testing in infertility treatment. This guideline is extremely relevant for fertility specialists and further insight into the topic is in high demand as the debate regarding the role of DNA damage testing is still...

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Clinical utility of sperm DNA fragmentation testing: concise practice recommendations

Sperm DNA integrity is generally acknowledged as an essential component for human reproduction. While the negative impact of high sperm DNA fragmentation (SDF) on outcomes of natural pregnancy and assisted reproductive technology (ART) is well known, the clinical indication of SDF testing is less well defined. A recent review on clinical utility of SDF testing highlighted the different SDF assa...

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Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for male fertility evaluation. While its detrimental implications on sperm function were extensively investigated, little is known about the actual indications for performing SDF analysis. This review delivers practice based recommendations on commonly encountered scenarios in the clinic. An illustrative descriptio...

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Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for male fertility evaluation. While its detrimental implications on sperm function were extensively investigated, little is known about the actual indications for performing SDF analysis. This review delivers practice based recommendations on commonly encountered scenarios in the clinic. An illustrative descriptio...

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Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Recent studies show that spermatozoal DNA integrity is essential for normal fertilization and transmission of paternal genetic information to the offspring. Additionally, fertilization and embryo development depend on the sperm DNA structure (1,2). Generally, while fertile men have high levels of sperm with intact DNA...

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ژورنال

عنوان ژورنال: Translational Andrology and Urology

سال: 2017

ISSN: 2223-4683,2223-4691

DOI: 10.21037/tau.2017.03.34